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Liver function tests (AST, ALT, bilirubin) and kidney function tests (creatinine, eGFR)

Retatrutide is a triple hormone receptor agonist that targets GLP-1, GIP, and glucagon receptors

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The STEP 8 trial: direct comparison The STEP 8 trial is the most important study for this comparison because it pitted semaglutide 2.4 mg weekly directly against liraglutide 3.0 mg daily in adults with overweight or obesity but without diabetes

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