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The two compounds work through entirely independent systems

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References: Prescription Fills for Semaglutide Products by Payment Method | Health Policy | JAMA Health Forum | JAMA Network Amylin brain circuitry ScienceDirect Infusion of the amylin antagonist AC 187 into the area postrema increases food intake in rats ScienceDirect Sustained Weight Loss Following 12-Month Pramlintide Treatment as an Adjunct to Lifestyle Intervention in Obesity | Diabetes Care | American Diabetes Association Eli Lillys experimental obesity drug shows over 11% weight loss in early trial | Reuters Chronic Weight Management Trial Results | Wegovy (semaglutide) Novo Nordisk presents phase 3 data for next-generation CagrilintideSemaglutide in Adults with Overweight or Obesity and Type 2 Diabetes | New England Journal of Medicine Roche to present new pivotal data at ASH 2021 from broad and comprehensive portfolio, challenging treatment standards for people with blood disorders Pfizer to Acquire Metsera and its Next-Generation Obesity Portfolio | Pfizer AstraZeneca Targets Obesity Market with Potential $2B Deal for Early GLP-1 Candidate BioSpace Pfizer Provides Update on Oral GLP-1 Receptor Agonist Danuglipron | Pfizer

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