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Therefore, establishing a hypoxia-induced endothelial cell senescence model is crucial for studying these diseases

Pancreatic -cells, in particular, have elevated zinc concentrations compared to other cell types

doi: 10.1194/jlr.D029546 174 ZhuMSunYSuYGuanWWangYHanJet al

Pancreatic acinar cells exhibit exceptionally high secretory activity and therefore depend on close spatial and functional coupling between mitochondria and the apical region enriched in zymogen granules (ZGs)

Zinc acts as a cofactor for the antioxidant enzyme superoxide dismutase (SOD), which protects cells from oxidative stress and damage