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While a balanced diet is important for overall health, factors such as nutrient absorption, individual metabolism, and lifestyle habits can impact nutrient levels

Moreover, key flavonoids such as quercetin (Khursheed et al., 2020) and fisetin (Szymczak and Cielecka-Piontek, 2023) exhibit extremely poor aqueous solubility and high lipophilicity, resulting in limited dispersibility in topical formulations and thereby potentially limiting skin permeation

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DOI: 10.1186/1758-5996-6-80 Nguyen, H., Pellegrini, M

L-ascorbic acids benefits can be attained through both diet and topical application

Huang C, Mattis P, Perrine K, Brown N, Dhawan V, Eidelberg D