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Head and neck cancer (HNC) In studies of HNC, two GPX 4 inhibitors, (1s, 3R)-RSL 3 and ML-162, were found to induce ferroptosis in HNC cells to varying degrees

Like other downstream targets of the insulin receptor, GS regulation involves a AKT/PKB-mediated inhibition of GSK3 which normally phosphorylates and inhibits GS

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