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According to the Mayo Clinic, current frontline options like tirzepatide (Zepbound/Mounjaro) and semaglutide (Wegovy/Ozempic) remain highly reliable, offering 15% to 22% weight loss with lower rates of gastrointestinal side effects

Preclinical and clinical studies suggest potential effects on bone metabolism, with evidence that GLP-1 receptor activation may support bone formation and remodeling

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The amniotic fluid index was significantly higher in the DS group (48.93 10.44 vs