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The regional selectivity for visceral and subcutaneous fat, combined with preservation of lean tissue, creates favorable conditions for body recomposition

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We attempted direct inhibition with KMV, but this was toxic to CD8 + T cells at concentrations needed to inhibit the OGDHc, as also observed in HeLa cells

Delayed gastric emptying extends their residence time in the stomach, but because the enteric coating protects the active compound, the net effect on bioavailability is minimal