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Kumpitsch, C., Koskinen, K., Schpf, V

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Whats interesting is that the profiles of BAs in patients with T2DM vary across different studies

While the liver was previously thought to be the main target of metformins glucose-lowering effects, recent evidence suggests that other parts of the body, such as the gastrointestinal tract, also play a role in its overall clinical advantages

For example, Streptomyces griseus NIOT-VKMA29, isolated from marine sediment, was found to produce L-ASNase at high yields, with optimization techniques enhancing its activity

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