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Here, we focus on the underlying mechanism of IR including direct defective of insulin signaling, epidemiological factors, interorgan metabolic crosstalk, metabolic mediators, genetic mutation, epigenetic dysregulation, non-coding RNAs, and gut microbiota dysbiosis

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They start churning out collagen and other proteins at an abnormal rate

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Such similarities underscore a possible common pathway of disease impact through mitochondrial compromise, enhancing our understanding of long COVIDs debilitating effects