What Other Studies Say Aside from observational studies in humans, some animal studies have something to say about vitamin B-12 and its correlation with weight loss
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Results from this study suggest that hepatic fat export in periparturient dairy cows is improved by choline supplementation during the transition period and this may potentially decrease the risk for metabolic disorders in the periparturient dairy cow.12 Choline is also known to be involved in the synthesis of carnitine, cell membrane phospholipids, and the neurotransmitter acetylcholine
Moreover, the amount of B12 in the liver reflects its metabolic requirements, not storage
The safety and effectiveness of continued long-term use in these individuals has not been established
People with diagnosed vitamin B12 deficiency or absorption issues should consider discussing injections with their healthcare provider