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doi: 10.15850/amj.v3n3.474 15 SmolenJSLandewRBMBijlsmaJWJBurmesterGRDougadosMKerschbaumerAet al

Anti-Inflammatory Action Downregulates pro-inflammatory cytokines (like TNF- and IL-6) while upregulating anti-inflammatory responses

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It does not regenerate cartilage that has been lost to years of mechanical wear

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The goal in the research framing is to establish continuous exposure across the early, most active repair window