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There will always be unmeasured confounders in observational data this is why a clinical trial is important to show causality, says McDonald

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For the UACR subgroup analyses, the model was stratified by CV risk group only because UACR was not measured in PIONEER 6 [6]

Researchers from Truveta, a health data analytics company, analyzed electronic health records for more than 18,000 adults, all of whom had overweight or obesity, who were using these medications in the real world between May 2022 and September 2023