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The subcutaneous route was selected due to the peptide nature of semaglutide, which limits oral bioavailability because of gastrointestinal enzymatic degradation
[DOI] [PubMed] [Google Scholar] 80.Wang MY, et al
Efficacy and safety of semaglutide once-weekly versus sitagliptin once-daily as add-on to metformin in subjects with type 2 diabetes (SUSTAIN - CHINA MRCT) (SUSTAIN)
In most cases, you should be able to continue using both the IUD and semaglutide without issues
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