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The C-terminus of the ligand first binds to the NTD, a process that is essential for the initial recognition of the ligand
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When mitochondrial function is impaired, it can lead to reduced energy availability, oxidative stress, and contributes to a range of metabolic disorders, including insulin resistance and obesity
10.1016/j.phrs.2019.104459 9 GuoD.MuW.ShenF.LiuY.LiuC.QianH
A GGT gene family exists in the human genome (Table I), suggesting that regulating GGT activity may be associated with activating different GGT genes rather than identifying distinct gene loci (26)
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