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Systemic symptoms such as upper respiratory tract infections, vomiting, persistent diarrhea and abdominal pain, respiratory failure, hyperlactatemia and hyperkalemia can also be present [16, 17]

The retatrutide versus semaglutide comparison highlights just how much more aggressive the weight loss trajectory may be, which could have implications for how aggressively providers prescribe to patients at lower BMI ranges

Ishii M, Nakamura T, Kasai F, Onuma T, Baba T, Takebe K