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In this study, which we planned with the hypothesis that oxidative stress parameters would be higher in OCD patients, we aimed to examine the levels of antioxidants CAT, SOD and total GSH and oxidative stress markers MDA and IMA in OCD patients and to investigate whether there is a relationship between oxidative parameters

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Furthermore, the pathogenesis and elevated risk of certain inflammatory processes, including obesity, are related to dysbiosis

Notably, in these studies, the upregulation of GPx4 has been achieved by using exogenous agents (like NVP-AUY922, Bafilomycin A1, PD151746, GsMTx4, epigallocatechin-3-gallate, total flavonoids of Engelhardia roxburghiana leaves, Lycium barbarum polysaccharide-glycoprotein, perillaldehyde, melotonin, ferulic acid, and sphingosine-1-phosphate) which either inhibit the degradation of GPx4 or increase its transcription by activating the Nrf2 [67]

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F2 and F4 showed sustained release biphasic release patterns that extended for 24 h