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Hear from our Chief Medical Officer, David Weinreich, about what this milestone means for patients

Focus is placed on mechanisms related to glucose homeostasis, energy expenditure, and lipid metabolism

A large number of clinical samples and animal experiments show that GPX4 levels are significantly decreased in degenerative cartilage tissue, and the degree of its downregulation correlates with the severity of articular cartilage destruction, matrix degradation, and inflammation (Miao et al., 2022

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Satisfying the increased demand for glutamine/glutamate is likely to be one of the critical requirements for the establishment of NRF2-addiction in cancer cells