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Understanding Sleep Mechanisms Cortistatin Well-defined receptor pharmacology (sst1-5 plus GHSR-1a) and clear mechanism of cortical synchronization make cortistatin a more tractable research target for sleep neurobiology Human Data Availability DSIP DSIP has been administered to humans in multiple studies dating to the 1980s, providing at least some clinical data

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Immunol Lett

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Research published in Ageing Research Reviews has explored the relationship between GHRH analogs, growth hormone secretion, and IGF-1 regulation, helping establish the physiological basis for their use in carefully selected patients (Merriam et al., 2003)