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Mechanism of Action: How Semaglutide Works Semaglutide operates by mimicking the actions of the naturally occurring hormone GLP-1 (glucagon-like peptide-1)

Twelve to fourteen weeks of use

Think of it like this: you still need to do the work, but the medication removes many of the barriers that typically derail weight loss efforts

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Research from ACR Convergence 2025 highlighted GLP-1 receptor agonists as showing particular promise in psoriatic arthritis management, where the dual burden of skin and joint disease creates challenges for conventional therapies

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