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It also plays a critical role in maintaining cellular health by directly neutralising free radicals, as well as by maintaining the activity of vitamins C and E

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The higher GSH levels in some tumor cells are also typically associated with higher levels of GSH-related enzymes and transporters

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The folate cycle and methionine cycle are two major components of this network required for regulating amino acid homeostasis, including the three amino acids that make up glutathione: cysteine, glycine, and glutamic acid