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Additionally, it has been suggested that GIPR agonists and antagonists might target different CNS receptor populations, with evidence showing that acylated peptide GIPR agonists act on GABAergic neurons to further reduce food intake and body weight when combined with GLP-1R agonists in mice 39,40

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Conclusion In conclusion, our study provides novel insights into the role of oxidative stress markers in Down syndrome and identifies NQO1 as a potential biomarker for prenatal screening

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Ueda et al