NAD+ levels naturally decline with age, and Brecka recommends supplementation to help maintain mitochondrial function and metabolic efficiency
Pickard JM, Zeng MY, Caruso R, Nez G (2017) Gut microbiota, Role in pathogen colonization, immune responses, and inflammatory disease
Erden, Y
The results of the SURE-PD trial revealed that treatment with inosine for up to 24 months was clinically safe and well-tolerated at doses that elevated serum UA concentrations from a mean of 4.5 mg/dL to 6.17.0 and 7.18.0 mg/dL [104]
Sahoo RK, Gupta T, Smily, Kumar V, Rani S, Gupta U
The response may enhance existing allergies or IgE responses to neo-allergens and susceptibility to respiratory infection