First thing in the morning on an empty stomach With no more than 4 ounces of plain water With no food, drink, or other medications for at least 30 minutes afterward Swallowed whole, without crushing or splitting The reason for these rules is that oral absorption of the medication is tricky thats why it took so long for a pill to be available, says Dan Azagury, MD, a weight loss physician and bariatric surgeon at Stanford Medicine in Palo Alto, California
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Anaphylactic shock after a single oral intake of acetazolamide
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The mechanism of bioactivation and antigen formation of amodiaquine in the rat