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Under normal circumstances, the intestinal mucosal barrier is equipped to handle mycotoxins without incurring damage

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The immune system may enter a chronic inflammatory state, reacting as if under constant threat

However, outcome from investigations using mice genetically manipulated for proteins integral or associated with the TJ have not been consistent and have resulted in diverse effects including immune adaptation and tolerance (summarized in Table 2)

Prat., 15:511-516 (2001) 7

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