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The mechanism is not fully understood but it is believed that the increased intracellular glutathione levels and increased ROS 217 are closely coupled with the build-up of toxic lipid peroxides and consequent ferroptosis
It has yet to be published in a peer-reviewed journal
Inhibition of COX-2/mPGES-1 and 5-LOX in macrophages by leonurine ameliorates monosodium urate crystal-induced inflammation
It is manageable
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Mnzel T, Keaney Jr JF
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