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Herein, we focus on the potential therapeutic effects of IGF-1 in NDD associated with MetS and the molecular mechanisms underlying its pharmacological effects

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For instance, AKT is activated due to PI3K mutations or PTEN deletions frequently found in cancer patients [85,86,87]

10.1186/1465-9921-14-7 46 HwangboH.KimM

Adicionalmente, estimula la sntesis de colgeno tipo I y III y acta como un potente agente antioxidante, contribuyendo a la neutralizacin de especies reactivas de oxgeno en modelos experimentales

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