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It is illustrated that the higher surface area of NPs is associated with more reactive sites on the surface, resulting in higher chemical reactivity to increase ROS generation (Wilson et al., 2002

[6] Our patient developed pigmentation later in childhood and there was no reticulate pigmentation which excludes this condition

B16-F10 cells were serum-starved and treated with 200 ng/mL or 500 ng/mL of mGH and incubated for 30 min at 37 C