Based on our data finding that SYNCRIP depletion increased ROS levels, we next examined mitochondrial function under SYNCRIP silencing
10.3390/foods13244109 [DOI] [PMC free article] [PubMed] [Google Scholar] Santo, R
2024 Jan 26;25(3):1517
Abnormalities in selenium metabolism and skeletal development diseases Selenium deficiency is regarded as one of the initiating factors of KBD, which is an endemic osteoarthropathy caused by the premature closure of epiphyseal plate and the impaired skeletal development
Further simulations showed that over a wide range of doxorubicin (050 M), the model can be used to suggest the specific concentration and exposure duration required to deplete cytosolic GSH by 70%, the threshold by which antioxidant defence is impaired, protein binding occurs, and cell death is possible
It may help gradually reduce the formation of darker melanin pigments, which could support a more even skin tone over time