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While no medication is without risks and side effects, semaglutide is relatively safe for most people
This article was written by Wichakorn Jitphaphun, M.D
Sittipo, P., Choi, J., Lee, S
Thats because it affects parts of the brain related to reward and habit
Cell 188 , 20432062 (2025)
Patients achieving a 5% reduction from baseline in body weight was a co-primary outcome in the STEP 1 to STEP 3 studies, and there were greater percentages of patients in the semaglutide group than in the placebo group who achieved a 5% weight loss by week 68 in each of STEP 1 (odds ratio [OR] = 11.22 [95% CI, 8.88 to 14.19
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