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Epigenetically, anti-aging methylation changes were strongly attenuated across these tissues, and the negative correlation between aging and treatment effects in the plasma metabolome was diminished

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in control: 91.1 15.2 mol/L), but higher levels of dehydroepiandrosterone (DHEA), testosterone, luteinizing hormone (LH), low-density lipoproteins (LDL) and fasting insulin compared to healthy women [36]