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Paavilainen E, et al

Mary's, and Prince George's counties

pmid:23494053 42

This study was funded by the National Natural Science Foundation of China (82474560, 82104914), the Natural Science Foundation of Shandong Province of China (ZR2023MH112), 2024 Shenzhen Luohu District Soft Science Research Program (LX202402023)

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Although genetic variations at these loci have long been considered neutral, the availability of a significant amount of epidemiological data and the use of mathematical models have allowed us to discover that some combinations of alleles at these loci may be subject to selection and that some combinations in some hypervirulent lines are associated with small gains in fitness for meningococcal transmission (Buckee et al., 2008)