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Moreover, while a few studies have conducted preliminary pharmacokinetic analyses (Hu et al., 2024), systematic evaluation of drug metabolism, long-term toxicity, and in vivo efficacy remains limited

The same transwell membranes can be applied for the modeling BCB (Schroten et al., 2012

These reactions often act to detoxify drugs (although in some cases the intermediates in drug metabolism may cause toxic effects)

PL 14736 A designation used in parts of the research literature

[DOI] [PubMed] [Google Scholar] 62.Toh S.Y., Zarshenas N., Jorgensen J

This broad pathophysiological impact underscores the necessity of holistic therapeutic strategies targeting both urate-lowering and anti-inflammatory mechanisms