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Prodrome signals the onset of an attack about a day or two in advance

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Certain groups have been excluded from trials or may face additional risks, including: People who are pregnant or breastfeeding , as the safety profile in these groups has not been established Individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) this exclusion reflects trial protocols and the US prescribing label for some GLP-1 receptor agonists

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They are more resistant to insulin signaling

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