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These data suggest that GSH synthesis, potentially through NRF2 repression, also limits NRF1 protein expression in the liver

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Glutathione synthetase

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As a key part of the bodys endogenous defense mechanism, the presence of glutathione neutralizes and reduces these free radicals.* The production of ROS increases with age, at the same time our internal defense mechanisms weaken, resulting in oxidative stress an imbalance where ROS outnumber antioxidants in the body