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Based on currently available clinical data, retatrutide has demonstrated some of the largest average weight loss outcomes among injectable weight loss medications

For someone already taking a GLP-1 medication, this reinforces the idea that obesity treatment is not cosmetic its a chronic disease treatment and risk-reduction medication. GLP-1s Users Had Lower Rates of Blood Clots, ER Visits, and Death The study analyzed health records from more than 26,000 adults with obesity and at least one autoimmune disease, such as rheumatoid arthritis, psoriatic arthritis, type 1 diabetes, vitiligo, and celiac disease

We performed two analyses looking at switching patterns across consecutive months (e.g., JanFeb 2025)

(2.1) o These formulations are not substitutable on a mg per mg basis o Use either formulation but do not use both formulations at the same time

If someone chooses to try a modified version (with protein and other whole foods included), keeping it to one to three days significantly reduces the nutritional risk compared to extended versions

Age plays a significant role, as collagen production naturally decreases after age 25, reducing the skins ability to bounce back