And so the to the extent that depending on the population and presentation, we can deliver, as much as double digit percentage reductions in weight will definitely lead to a reduction in comorbidities, improved health
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Thinning around the temples
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This finding highlights not only the key role that mitochondrial metabolism has in modulating response and resistance to TS inhibitors, but the wider opportunity afforded to enhance TS inhibitor-mediated anti-cancer effects by targeting mitochondrial metabolism using metformin or other compounds with similar mitochondrial impact
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