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doi:10.1111/j.1471-0528.1968.tb02022.x

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This analysis gives researchers confidence in their data and supports reproducibility required for publications and peer review

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They should be carefully administered to patients with risks of hypovolemia (older age, cardiovascular diseases, treatment with diuretics, liver cirrhosis with circulatory dysfunction)

It is important to note that ebselen mimics the activities of all the selenium-dependent mammalian GPXs, not only to GPX1, and has other effects on redox status