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Injectable GLP-1s may be more suitable for: Patients aiming for the maximum possible reduction in body weight, those with co-existing conditions like heart disease or chronic kidney disease (due to specific FDA approvals for Ozempic), or those who prefer a simple weekly medication schedule

Manufacturers with late-stage biologics should model PBM private-label biosimilar competition at LOE as a baseline scenario, not an edge case

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CKD , chronic kidney disease