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Nofreezing denatures the peptide structure and renders tirzepatide ineffective
Completed cards were returned and collected by the investigator at each visit
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We showed that cirrhotic (an IGF-1 deficiency condition) rats had diminished amino acid and glucose intestinal absorption [114, 194, 195] and that IGF-1 replacement therapy was able to restore both alterations, suggesting a role of IGF-1 in the position of transporters [196]
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