Quitting semaglutide could result in weight gain
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As a result, these effects often fade
PPI safety for long-term use Extended PPI use (longer than 8 weeks at full dose) carries potential risks including magnesium depletion, B12 deficiency, slightly increased fracture risk, and possible kidney effects
This is in line with Phase II study results for semaglutide treatment in participants with type 2 diabetes, with 11% of total participants withdrawing from the trial due to AEs (vs 12.9% in the present study), primarily due to GI AEs in the first month of treatment [16]
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