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[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Ibarrola P., Blackwood L., Graham P.A., Evans H., German A.J

Vitamin B12 deficiency, left untreated, can lead to pernicious anaemia or neurological problems

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If these intermediates build up faster than the Krebs cycle can process them, they become highly toxic, effectively choking the mitochondria and halting the entire energy-producing apparatus

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Despite the efforts to understand the role of UA in the pathogenesis of inflammatory diseases, it is presently unclear whether UA oxidation products could modulate such intracellular redox signalling pathways