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Erectile dysfunction (ED) is the consistent difficulty in achieving or maintaining an erection firm enough for sexual activity

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Such as depression, continual exhaustion, memory loss, and anemia

Constipation can also begin during this phase, though it is less common at the starting dose

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In the Phase 2 trial, starting at a lower dose (2 mg versus 4 mg) significantly reduced the incidence and severity of gastrointestinal adverse events without compromising weight-loss outcomes