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I dont see why its effects on thyroid would change due to the route but who knows

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Platelet-Rich Fibrin (PRF) Hair Restoration PRF is a next-generation regenerative treatment derived from the patients own blood, containing a high concentration of platelets, growth factors, and fibrin matrix

doi: 10.3390/biomedicines10061242 [DOI] [PMC free article] [PubMed] [Google Scholar] 143