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The proposed mechanisms involve enhanced perfusion to injured tissues, modulation of inflammatory responses, and promotion of satellite cell activation and myogenesis

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Upon IN administration, they undergo sol-gel phase transformation at the nasal pH of ~6.2 and form a three-dimensional gel structure [28,29,30]

Injecting the water stream directly onto the lyophilized powder can physically damage the delicate molecular structure from the force of the pressure

Increases in dermal collagen and improved hydration likely underlie these effects

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