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To validate the functional role of the RAPTORmembrane interaction, we tested the RAPTOR F1296E and RAPTOR F1296E/M1297E constructs in inducible RAPTOR knockout mouse embryonic fibroblasts (MEFs) (Fig

Heatmap showing fold change in metabolite levels (log 2 ) of the indicated cell lines relative to the average of those in SLC25A39 knockout cells complemented with SLC25A39 cDNA (middle)

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doi: 10.1158/1078-0432.CCR-11-2776 349 BaeJPrabhalaRVoskertchianABrownAMaguireCRichardsonPet al

SCFAs also contribute to chromatin remodeling by stabilizing accessibility at anti-inflammatory gene regions (156)

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