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In animal models, glial cells such as astrocytes and NG2 oligodendrocyte precursor cells can be directly converted into functional neurons in vivo via ectopic expression of neurogenic transcription factors like NeuroD1 and Ascl1

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Lack of response may indicate incorrect diagnosis, concurrent deficiencies, or inadequate treatment frequency

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Trends Neurosci 26 : 184192

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136 1701-1705 (American Institute of Nutrition, 2006)

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