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The primary mechanism involves intrinsic factor binding in the stomach, while a secondary pathway allows small amounts to absorb through passive diffusion

This means that the vitamin is immediately available for the body to use without the need for complex digestion and absorption processes

Interestingly, much of the research has been based on doses far exceeding the recommended daily intake, both in individuals with pathological conditions and in healthy subjects

This broader hormonal response may support stronger weight management outcomes

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