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Updated on April 7, 2023 Article Summary Irritable bowel syndrome is associated with a wide range of uncomfortable symptoms that are poorly controlled with conventional therapies Although no single cause of IBS has been identified, researchers believe that inflammation plays a significant role

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However, a consensus regarding the clinical significance of reduced T3 and whether this should be corrected is unknown (5, 41).Evidence from clinical trials of LT4+LT3 combination therapy is mixed