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Another population-based cohort study of patients with T2DM with a concomitant cancer showed that no increased risk of metastasis was associated with DPP-4 inhibitor therapy (Noh et al., 2019)

Avoid any administration outside approved research contexts

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Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy