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Foundational NNMT Discoveries The foundational research establishing NNMT as a metabolic regulator and potential therapeutic target came from studies by Daniel Kraus and colleagues published in Nature in 2014, which demonstrated that NNMT expression is dramatically upregulated in adipose tissue of obese humans and diet-induced obese mice, and that genetic knockdown of NNMT in mice protected against diet-induced obesity and improved metabolic parameters

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Article Cited Ruetz Markus, Shanmuganathan Aranganathan, Gherasim Carmen, Karasik Agnes, Salchner Robert, Kieninger Christoph, Wurst Klaus, Banerjee Ruma, et al

Most of these side effects do not require medical attention and gradually resolve over time

Rotate injection sites to prevent irritation

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